Nearly all faculty members are engaged in clinical or basic neuroscience research. Residents are encouraged to participate in research.
Kris Bujarski, MD
- A Study of Inhibitory Interneurons (NRTX-1001) in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (MTLE).
- Human Intracranial Electrophysiology
George Culler, MD
- A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of RAP-219 in Adult Participants with Focal Seizures
- Retrospective case review of patients undergoing lumbar spinal surgery with erector spinae plane block (ESPB) and concurrent intraoperative neurophysiological monitoring (IONM)
Mary Feldman, DO
- "A Phase II, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate The Efficacy, Safety, And Pharmacokinetics of RO7568282 in Participants With Early Stage Parkinsons Disease"
Brian Fidali, MD
- SONATA: Self-administered ONe-of -a kind Approach to Epilepsy Therapy through Web-based Music Application
Mark Garret, MD
- Access for All in ALS (ALL ALS) - ASSESS
- Access for All in ALS (ALL ALS) - PREVENT
- ALS Platform Regimen-Specific Appendix I for NUZ-001
- Comparing the Impact of Video Integration to Traditional Amyotrophic Lateral Sclerosis Visit Communication on Patient and Caregiver Quality of Life (VITALS trial)
- HEALEY ALS Platform Trial - Master Protocol
- Intrathecal anti-sense oligonucleotide drug for patients with TARDBP ALS
- The impact of GLP-1 medicine in ALS: a multicenter chart review study
- The Pison Digital Biomarker for ALS
Francesca Gilli, MS, PhD
- Cerebral Spinal Fluid Bank for Research
- Contamination of single-cell RNA sequencing data by extracellular vesicles: a potential early disease biomarker for multiple sclerosis
- Single-cell and network analyses to unravel Multiple Sclerosis inflammation complexity
Anas Hannoun, MD
- Automated selection of the optimal active deep brain stimulation (DBS) settings in patients with idiopathic Parkinson's disease (IPD) using mathematical modelling based on presurgical and post-surgical imaging.
- Comparing EMG only vs EMG + US guided Botulinum toxin injections for essential tremor.
- Machine Learning in Clinical Parkinsonism Deferential Diagnosis
- Using mathematical quantification of limb and eye movement of Parkinson's disease patients as a biomarker for classification and prediction of disease state and response to treatment.
Barbara Jobst, MD
- A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Parallel-Group Study to Evaluate the Efficacy, Safety, and Tolerability of SPN-817 in Adults with Focal Onset Seizures
- A Multi-center, Phase 1/2a, First-in-human (FIH) Study Investigating the Safety, Tolerability, and Efficacy of AMT-260 in Adults with Unilateral Refractory Mesial Temporal Lobe Epilepsy (MTLE) Administered via Magnetic Resonance Imaging (MRI)-guided Convection-enhanced Delivery (CED)
- Evaluating the clinical course of patients with epilepsy
- HOBSCOTCH: HOme Based Self-management and COgnitive Training CHanges Lives
- HOme-Based Self-management and COgnitive Training CHanges lives (HOBSCOTCH) - Post-Traumatic Epilepsy (PTE)
- Mining neurostimulation parameters from RNS System data
- Multicenter Retrospective Study of Neocortical Patients with the RNS System: What is the Role of the Epileptogenic Zone?
- Network dynamics in human epilepsy: a retrospective investigation on intracranial EEG
- Retrospective SUDEP at Epilepsy Centers: A Case-Control Study
- Shared Subcortical Arousal Systems Across Perceptual Modalities
Anna Karpenko, MD
- "An Open-Label Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Efficacy, and Safety of a Single Dose of ANX005 in Participants with Guillain-Barré Syndrome"
Joshua Keegan, MD
- SSEP monitoring in refractory status epilepticus
Victoria Lawson, MD
- "A Double-blind, Randomized, Multi-Center Study Investigating Efficacy and Safety of Two Different Dosages of Intravenous Human Normal Immune Globulin (IGIV) 10% in Subjects with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)"
- "A Phase 1b/2a Double Blind, Randomized, Placebo Controlled Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Efficacy of CNP-106 in Subjects Ages 18-75 with Generalized Myasthenia Gravis"
- A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study To Evaluate The Efficacy And Safety Of DNTH103 In Adults With Chronic Inflammatory Demyelinating Polyneuropathy (Captivate)
- "Amended Disease Observational Study Protocol No.11 Rare Disease Registry- Cross-Registry Protocol"
- PPD CorEvitas Myasthenia Gravis (MG) Drug Safety and Effectiveness Registry
Stephen Lee, MD, PhD
- "A Phase 2/3, Double-Blind, Placebo-Controlled Study of BHV-8000 in Participants with Early Parkinson’s Disease"
- A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study To Evaluate The Efficacy And Safety Of Intravenous Prasinezumab In Participants With Early Parkinson’s Disease
- An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons with REM Sleep Behavior Disorder (RBD)
- An open-label extension of Study M15-741 to evaluate the safety and tolerability of 24-hour daily exposure of continuous subcutaneous infusion of ABBV-951 in subjects with Parkinson's disease
- Clinical Manifestations of Inflammasome Activity in PD
- Efficacy of Asleep VIM DBS Implantation Compared with Awake MER-guided Surgery
Timothy Lukovits, MD
- A multicenter, randomized, placebo controlled, double-blind, parallel group and event driven Phase 3 study of the oral FXIa inhibitor asundexian (BAY 2433334) for the secondary prevention of ischemic stroke in adult patients with an acute non-cardioemboli
- A Pilot Study on the Technical Feasibility of a Bioimpedance-based Intracranial Monitoring Device for Acute Stroke Care
- Neuro-AFib Study Retrospective Phase (Phase I) Data Abstraction Protocol
- Using Transcranial Doppler Ultrasound to Characterize the Role of Micro-emboli in Patients with Stroke and Concurrent Atrial Fibrillation (AF)
Richard Morse, MD
- "Carisbamate Expanded Access Program (EAP) For Patients With Lennox-Gastaut Syndrome (LGS)"
Nicole Odom, MD
- Understanding and improving mortality in epilepsy in a rural setting
Andrew Pachner, MD
- CXCL13 index as a predictive biomarker in clinically isolated syndrome-a biobank study (BI-CIS)
Jared Quast, MD
- Epileptiform Potential of Fully Immersive Virtual Reality
Diana Rojas-Soto, MD
- Rural Stroke Outcomes
Lara Ronan, MD
- Creative Arts Interventions for Improved Epilepsy Patient Quality of Life
Lindsay Schommer, MSN, APRN
- Suicide Prevention in Epilepsy: Development of a Disease Specific Model
- The feasibility of project uplift for the treatment of psychogenic non-epileptic seizures
Yinchen Song, PhD
- Utility of intraoperative neurophysiological monitoring (IONM) during transcarotid artery revascularization (TCAR) procedure
Elijah Stommel, MD, PhD
- ALS Gene x Environment x Time Interaction Analysis
- Case-control and Population Questionnaire Studying Environmental Risk Factors and Neurological Diseases
- Development and Characterization of a hiPSC-derived Neuronal Organoid Model of ALS
- Electrical impedance myography via the Myolex mScan as an ALS biomarker
- Geospatial and Toxicological Study of Massachusetts ALS Registry Patients
- Intermediate-Size Patient Population Expanded Access Protocol for SPG302 in Adult Patients with Amyotrophic Lateral Sclerosis (ALS)
- Neurological Disease Risk Analysis: Residential Proximity to Environmental Hazards
- Northern New England Neurologic Biospecimen Repository
- Use of Collected Biospecimens for the Detection of Toxins and Preliminary Genetic Analyses in ALS
Rebecca Thompson, MD
- "A randomized, placebo-controlled, double-blind Phase 3 study to evaluate the efficacy, safety and tolerability of votoplam in participants with Huntington’s Disease"
Elaine Wilson, MD
- HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer)
- HOBSCOTCH-YOUTH and Young Adults
- HOme-Based Self-management and COgnitive Training CHanges lives (HOBSCOTCH) – Multiple Sclerosis (MS)
- HOme-Based Self-management and COgnitive Training CHanges lives (HOBSCOTCH) Multiple Sclerosis (MS) Efficacy Trial
- HOme-Based Self-management and COgnitive Training CHanges lives (HOBSCOTCH)-Parkinson’s Disease (HOBSCOTCH-Parkinson’s)
- Managing Epilepsy Stigma in Primary Care Practice: A Quality Improvement Project
- Piloting A Telehealth Deliverable Self-Management and Cognitive Training Program (HOBSCOTCH, HOme Based Self-Management and COgnitive Training CHanges Lives) for People with Post Acute COVID Syndrome (PACS)
- Reducing Internalized Stigma in Epilepsy