Research and Scholarly Activity

Research groups and centers

  • Juliette Madan, MD (Former resident)
    Dr. Madan received support from the Psychiatry Department to start a new research based clinic in the novel area of neuroinflammation. She has teamed up with a pediatric neurologist and senior child psychiatrist at Dartmouth Hitchcock Medical Center to create a multidisciplinary clinic within child psychiatry to see children with autoimmune and inflammatory mediated neuropsychiatric disorders. She and her team have included several of the psychiatry and pediatric residents and fellows, in both clinical care and in research endeavors.

  • National Center for PTSD
    This center, located at the White River Junction, Vermont, brings together expertise in research and clinical care in PTSD.

  • The Center for Neuroscience
    This interdisciplinary group focuses on education and research, drawing on basic science, clinical, and cognitive behavioral neuroscience. Psychiatry residents may work in both basic science and applied research settings with outstanding mentors.

  • Center for Technology and Behavioral Health
    Informing and enhancing the development, evaluation, and implementation of novel technology-based interventions for substance-use and related disorders.

  • Northeast Node
    A research partnership in which the National Institute on Drug Abuse, researchers, and community-based providers develop, evaluate, and disseminate new prevention and treatment options for substance use disorders in community-based medical settings in Maine, New Hampshire, and Vermont.

  • Dartmouth Trauma Interventions Research Center

  • Moms in Recovery Research Study

  • Brain Research Network

  • Brain Imaging Lab in Psychiatry

  • Dartmouth Autism Research Initiative

Resident awards

  • Patrick Ho, MD
    • New Hampshire Young Professional of the year Award, 2020
    • Outstanding Service Award, 2021
  • Thara Nagarajan, MD
    • NNCI scholar 2019-2021
    • AADPRT national meeting 1st place poster winner, 2021
    • APA diversity Fellowship Award, 2020-2021
    • Outstanding Service Award, 2021
  • Michael Benson, MD
    • Gold Humanism teaching award for excellence in medical student teaching, 2020
  • Matthew Rasmussen, MD
    • Clinical Excellence Award, 2021
  • Melissa Ley-Thomson, MD
    • Clinical Excellence Award, 2021
  • Eric Bland, MD
    • Matthew S. T. Winer M.D. Award for Humanism & Excellence in Community Psychiatry, 2021
  • Gregory Alberto, MD
    • Honorable Mention NIMH ORAP award, 2021
    • First author publication in Nature Communications journal, 2021
  • Oakland Walters, MD
    • TDI certificate scholarship, 2019-2020
    • New Hampshire Psychiatric Society Poster Competition 1st place, 2020

Dartmouth Hitchcock Medical Center and New Hampshire Hospital-based teaching faculty research areas

William Torrey, MD Services Research
Luke Archibald, MD Site PI for CTN-100: Optimizing Retention, Duration, and Discontinuation Strategies for Opioid User Disorder Pharmacotherapy
H. Samuel Landsman, MD Proof of concept project for buprenorphine microinduction
Michael Kisicki, MD

Lifestyle practices in treatment of depression of teens. The role of imposter syndrome in medical trainee burnout.

Robert Roth, PhD Executive functions in health and illness. Test development.
Wilder Doucette, MD Computational approaches to determine how brain activity biomarkers could be used to individualize treatment selection and implementation using rodent models of addiction and related transdiagnostic domains of function.
Julia Frew, MD Perinatal psychiatry and perinatal substance use disorders, specifically models of integrated care for pregnant and parenting women with substance use disorder. Involved in creation of the National Curriculum in Reproductive Psychiatry (NCRP) and an offshoot of this curriculum designed for OB/Gyn trainees and providers.
Christine Finn, MD Consultation related topics
William Keller, MD Psychiatrist Study Physician
Julia Knight, MD Proof of concept study in collaboration with neurology department regarding use of TMS for treatment of depression in patients with co-morbid seizure disorder
Gary Moak, MD

1. Qualitative study of attitudes about aging among older adults with severe mental illness. 2. Design for study on frailty among older adults in a state mental hospital.

Robert Brady, PhD Development and evaluation of brief psychosocial interventions delivered in non-traditional mental health settings (e.g., primary care) by lay providers. The goal of this research is to support implementation and access to evidence-based practices for common mental health problems.
Keri Height, PsyD Substance use disorder treatment
John Hinck, MD Implementation of the STRIDE Weight Loss and Lifestyle Intervention at New Hampshire Hospital.
Aliaksandr Shakhau, MD Frailty in older adults with SMI.
Mary Brunette, MD Novel research program aimed at harnessing digital innovation to improve and expand treatment for tobacco use disorder in people with SMI

Research faculty VAMC White River Junction

  • Max Levis, PhD – Suicide prediction using electronic records; diagnostic assessment; and mental health promotion with online tools.
  • Natalie Riblet, MD, MPH – Suicide prevention in the post-discharge period.
  • Vince Watts, MD, MPH – rTMS as a stand-alone PTSD treatment; the relationship between effective mental health treatments; suicide in real-world practice.
  • Brian Shiner, MD, MPH – Quality and effectiveness of treatment for PTSD; suicide prevention in real-world practice.
  • Paul Holtzheimer, MD, MS – Somatic treatments for PTSD and depression; biomarkers of treatment response.
  • Lauren Sippel, PhD – Medication-assisted psychotherapy
  • Nancy Bernardy, PhD – Improving quality of rural PTSD care
  • Paula Schnurr, PhD – Large pragmatic trials of PTSD treatments and shared decision making for PTSD
  • Matt Friedman, MD, PhD – National brain banking studies of the genetic basis of PTSD and TBI pathology
  • Jessica Hamblen, PhD – Use of educational tools to promote engagement in PTSD care
  • Krystal Noller, PhD – Mechanisms of TBI pathology in blast injury
  • Yinong Young-Xu, ScD, MS, MA – Pharmaco-epidemiology and causal analysis, including studies of psychotropics, antivirals, and vaccines

Sampling of recent resident scholarly activity

Larger Initial Opioid Prescriptions Following Total Joint Arthroplasty Are Associated with Greater Risk of Prolonged Use.
Ruddell JH, Reid DBC, Shah KN, Shapiro BH, Akelman E, Cohen EM, Daniels AH.
J Bone Joint Surg Am. 2021 Jan 20;103(2):106-114. doi: 10.2106/JBJS.20.00732.
PMID: 33074953

Is Opioid-Limiting Legislation Effective for Hand Surgery Patients?
Shah KN, Reid DBC, Ruddell JH, Shapiro BH, James P, Gil JA, Daniels AH, Akelman E.
Hand (N Y). 2021 Feb 3:1558944720988132. doi: 10.1177/1558944720988132. Online ahead of print.
PMID: 33530762

Correction to: Psychological experience and coping strategies of patients in the Northeast US delaying care for infertility during the COVID-19 pandemic.
Seifer DB, Petok WD, Agrawal A, Glenn TL, Bayer AH, Witt BR, Burgin BD, Lieman HJ.
Reprod Biol Endocrinol. 2021 Apr 28;19(1):66. doi: 10.1186/s12958-021-00746-9.
PMID: 33910567

Provider Satisfaction from a New Telepsychiatry Inpatient Consultation Service. Yoon MS, Martin KB, Marraccini RL, Norris ER.
Telemed J E Health. 2021 Jan 20. doi: 10.1089/tmj.2020.0317. Online ahead of print.
PMID: 33471599

Rich Club Characteristics of Alcohol-Naïve Functional Brain Networks Predict Future Drinking Phenotypes in Rhesus Macaques.
Rowland JA, Stapleton-Kotloski JR, Alberto GE, Davenport AT, Epperly PM, Godwin DW, Daunais JB
Front Behav Neurosci. 2021 Jun 2;15:673151. doi: 10.3389/fnbeh.2021.673151. eCollection 2021.
PMID: 34149371

Narrative Reflections on the Role of Psychiatry Residents in the Early Days of the COVID-19 Pandemic.
Alberto GE, Rosen BJ, Ho PA.
Acad Psychiatry. 2020 Dec;44(6):679-680. doi: 10.1007/s40596-020-01288-9. Epub 2020 Jul 22.
PMID: 32700237

Envisioning a future for transgender and gender-diverse people beyond the DSM.
Perlson JE, Walters OC, Keuroghlian AS.
Br J Psychiatry. 2020 Jun 25:1-2. doi: 10.1192/bjp.2020.124. Online ahead of print.
PMID: 32583756

Taking the Lead: Lessons Learned by a Resident President.
Ho PA.
Psychiatr Serv. 2020 Oct 1;71(10):1082-1083. doi: 10.1176/ Epub 2020 Aug 4.
PMID: 32746715

Advancing Medical Education Through Innovations in Teaching During the COVID-19 Pandemic.
Ho PA, Girgis C, Rustad JK, Noordsy D, Stern TA.
Prim Care Companion CNS Disord. 2021 Feb 18;23(1):20nr02847. doi: 10.4088/PCC.20nr02847.
PMID: 34000143

Flattening the Mental Health Curve: COVID-19 Stay-at-Home Orders Are Associated With Alterations in Mental Health Search Behavior in the United States.
Jacobson NC, Lekkas D, Price G, Heinz MV, Song M, O'Malley AJ, Barr PJ.
JMIR Ment Health. 2020 Jun 1;7(6):e19347. doi: 10.2196/19347.
PMID: 32459186

Predictive modeling of depression and anxiety using electronic health records and a novel machine learning approach with artificial intelligence.
Nemesure MD, Heinz MV, Huang R, Jacobson NC.
Sci Rep. 2021 Jan 21;11(1):1980. doi: 10.1038/s41598-021-81368-4.
PMID: 33479383

Impact of online mental health screening tools on help-seeking, care receipt, and suicidal ideation and suicidal intent: Evidence from internet search behavior in a large U.S. cohort.
Jacobson NC, Yom-Tov E, Lekkas D, Heinz M, Liu L, Barr PJ.
J Psychiatr Res. 2020 Nov 9:S0022-3956(20)31069-4. doi: 10.1016/j.jpsychires.2020.11.010. Online ahead of print.
PMID: 33199054

The infant gut resistome is associated with E. coli and early-life exposures.
Lebeaux RM, Coker MO, Dade EF, Palys TJ, Morrison HG, Ross BD, Baker ER, Karagas MR, Madan JC, Hoen AG.Lebeaux RM, et al. BMC Microbiol. 2021 Jul 2;21(1):201. doi: 10.1186/s12866-021-02129-x.BMC Microbiol. 2021. PMID: 34215179

Infant Feeding Alters the Longitudinal Impact of Birth Mode on the Development of the Gut Microbiota in the First Year of Life.
Coker MO, Laue HE, Hoen AG, Hilliard M, Dade E, Li Z, Palys T, Morrison HG, Baker E, Karagas MR, Madan JC. Microbiol. 2021 Apr 7;12:642197. doi: 10.3389/fmicb.2021.642197. eCollection 2021.Front Microbiol. 2021. PMID: 33897650

Information enhanced model selection for Gaussian graphical model with application to metabolomic data.
Zhou J, Hoen AG, Mcritchie S, Pathmasiri W, Viles WD, Nguyen QP, Madan JC, Dade E, Karagas MR, Gui J.Zhou J, et al. Biostatistics. 2021 Mar 15:kxab006. doi: 10.1093/biostatistics/kxab006. Online ahead of print.Biostatistics. 2021. PMID: 33720330

Racial and geographic variation in effects of maternal education and neighborhood-level measures of socioeconomic status on gestational age at birth: Findings from the ECHO cohorts.
Dunlop AL, Essalmi AG, Alvalos L, Breton C, Camargo CA, Cowell WJ, Dabelea D, Dager SR, Duarte C, Elliott A, Fichorova R, Gern J, Hedderson MM, Thepaksorn EH, Huddleston K, Karagas MR, Kleinman K, Leve L, Li X, Li Y, Litonjua A, Ludena-Rodriguez Y, Madan JC, Nino JM, McEvoy C, O'Connor TG, Padula AM, Paneth N, Perera F, Sathyanarayana S, Schmidt RJ, Schultz RT, Snowden J, Stanford JB, Trasande L, Volk HE, Wheaton W, Wright RJ, McGrath M; program collaborators for Environmental Influences on Child Health Outcomes.Dunlop AL, et al. PLoS One. 2021 Jan 8;16(1):e0245064. doi: 10.1371/journal.pone.0245064. PMID: 33418560

Identification of microbial interaction network: zero-inflated latent Ising model based approach.
Zhou J, Viles WD, Lu B, Li Z, Madan JC, Karagas MR, Gui J, Hoen AG.Zhou J, et al. BioData Min. 2020 Oct 7;13:16. doi: 10.1186/s13040-020-00226-7. eCollection 2020.BioData Min. 2020. PMID: 33042226

Prospective associations of the infant gut microbiome and microbial function with social behaviors related to autism at age 3 years.
Laue HE, Korrick SA, Baker ER, Karagas MR, Madan JC.Laue HE, et al. Sci Rep. 2020 Sep 23;10(1):15515. doi: 10.1038/s41598-020-72386-9.Sci Rep. 2020. PMID: 32968156

MEG source imaging detects optogenetically-induced activity in cortical and subcortical networks.
Alberto, G.E., Stapleton-Kotloski, J.R., Klorig, D.C., Rogers, E.R., Constantinidis, C., Duanais, J.B., Godwin, D.W. Nature Communications. In press.